Product Name :
NgR3 Recombinant Rabbit Monoclonal Antibody [JE64-44]
Predicted band size :
49 kDa
Observed band size :
49 kDa
Synonyms:
DKFZp547J144 antibody NgR 3 antibody NgR3 antibody NGRH 2 antibody NGRH2 antibody NGRL2 antibody Nogo 66 receptor homolog 2 antibody Nogo 66 receptor related protein 3 antibody Nogo receptor like 2 antibody Nogo receptor-like 2 antibody 展开
Function :
Cell surface receptor. Plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG. Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans. Binds heparin (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human NgR3 aa 351-400 / 441.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P
Coupling :
unconjugated
Clone number:
JE64-44
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.1240597-30-1 structure Aliquot store at -20℃.1205671-72-2 Chemscene Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.PMID:33491154 4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 49 kDa
Positive control :
SH-SY5Y cell lysate, K-562 cell lysate, RAW264.7 cell lysate, C6 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, C6, human brain tissue, mouse brain tissue, rat brain tissue.